Male piglets have been castrated for centuries to avoid contamination of their meat with boar taint, a strongly unpleasant odour that makes the meat inedible. Today boar taint can be prohib-ited by vaccination against gonadotropin releasing hormone (GnRH) using Improvac®. The aim of this study was to evaluate the efficiency of vaccination on growth performance and behaviour of vaccinated male pigs compared to surgically castrated male pigs. The effect of two feeding regimes, restricted (SLU-norm) and semi ad libitum, was also included in the study. At birth, pigs (n=206) were randomly allocated to the two treatment groups; surgically castrated and vaccination.

Immunisering mot gonadotropin-releasing hormone (GnRH) har visat sig vara effektivt mot att hämma galtlukt på griskött och oönskat aggressivt beteende bland hangrisar. I ett samhälle där vi sätter allt högre krav på våra produktionsdjurs välfärd är efterfrågan på metoder som inte innebär smärta eller lidande för djuren stor. Det finns dessutom positiva produktionsrelaterade effekter med immunokastrering gentemot klassisk kirurgisk kastrering, såsom ökad tillväxtpotential. Faktorer som dessa talar för immunokastrering, men samtidigt finns många svårigheter med att vaccinera mot något kroppseget och således bryta kroppens tolernas mot självt. Den här litteraturstudien behandlar svårigheterna med att rikta ett vaccin mot ett endogent hormon, vad som har lett fram till dagens upptäckter och de eventuella problem som kan uppstå i framtiden.

Hundreds of thousands of piglets are castrated without anesthesia in Sweden every year so that we may be guaranteed meat without boar odor. The smell appears while cooking meat of boar and is described as urine- and sweat-like. High levels of androstenone and skatole are considered the main factors behind boar odor. Skatole is a metabolite of the amino acid tryptophan, which is formed in the colon of all pigs. Androstenone is a steroid hormone that is released from the Leydig cells in the testes of boars.

Active immunization against gonadotropin-releasing hormone (GnRH) is an alternative to surgical castration of male pigs to avoid boar taint. The aim of this study, including 128 pigs, was to evaluate the effect of a GnRH-vaccine Improvac® on performance and on social and sexual behaviour. Male pigs were assigned to three treatments; surgical castration at four days of age, immunization against GnRH and no castration. Vaccination was performed eight and four weeks before slaughter. Surgically castrated male pigs had significantly lower daily weight gain during the suckling period than entire male pigs (235 vs.

Studien jämför tre grupper av farmakologiska preparat som kan åstadkomma kontroll av östrus hos honkatt, progestiner, GnRH-agonister och melatonin. Progestiner är hormoner som verkar kontraceptivt genom att ge negativ feedback på både hypofysen och hypotalamus. Vid behandling med progestiner minskar östrogen- och progesteronnivåer. GnRH-agonister liknar det naturliga hormonet GnRH. Ständiga GnRH-påslag desensibiliserar hypofysen och GnRH-receptorerna nedregleras vilket leder till att det endogena GnRH blir verkningslöst, och varken LH eller FSH kan frisättas. Melatonin är ett naturligt hormon som påverkar dygns- och årsrytmen. Vid kontiuerligt melatoninpåslag luras det endokrina systemet in i en årstidsbunden anöstrus. Efter en kort bakgrund om vikten av en effektiv, reversibel östrushämning och en översikt av honkattens reproduktion redovisas fakta om de tre farmakologiska substanserna. Aspekter som tas i beaktande är främst användarvänlighet och biverkningar.

This study has been made to evaluate if there is a significant difference between non-estral intact versus ovariohysterectomized queens in their production of estradiol after exogenous gonadotrophin-releasing hormone stimulation. The purpose is to find a tool, which can help to diagnose if a free-roaming queen is already ovariohysterectomized or not. There are also other situations where this tool could be useful, for example to diagnose the ovarian remnant syndrome. Previous studies in bitches have shown that GnRH-stimulation is an excellent tool to diagnose the presence of ovaries in the bitch. Eleven ovariohysterectomized and eleven intact queens have been included in this study where we have analyzed plasma estradiol and progesterone concentrations before and after a single intramuscular injection of the GnRH agonist buserelin (Receptal?).

Vaccination är en av de mest kostnadseffektiva åtgärderna inom sjukvården. Sveriges vaccinationsprogram innefattar tio sjukdomar och barnets femte dos ges vid fem års ålder. Barn i förskoleåldern befinner sig i ett utvecklingsstadium vilket kan försvåra vaccination. Tidigare studier beskriver svårigheter och den stress sjuksköterskor upplever i samband med vaccination av barn, kunskapsbrist finns däremot kring hur barnen bör hanteras. Syftet med studien var att utifrån betydelsefulla händelser beskriva barnhälsovårdssköterskans (BHVsköterskans) erfarenheter och agerande vid vaccination av förskolebarn som inte vill medverka.

Background: Vaccination is an important part in cats? welfare. It both helps to prevent the individual cat from catching a disease or lessen the symptoms of it, and protects the entire cat population from an epidemic. It is the cat owner who makes the decision to vaccinate or not. Understanding the cat owners? perspective regarding vaccination may improve communication between the owner and the veterinary nurse, which may lead to a higher vaccination rate among cats.

Vaccination as a part of the preventative public health project has for many years been one of the important tasks of the children's health care. The vaccination program has been adjusted to current research and the health situation in the country. Having their children vaccinated is not something obvious for all parents, though. Especially the vaccination against measles, whooping cough and German measles have been questioned. The purpose of this literature study was to investigate the reasons for the resistance to vaccinate and to illuminate the security creating advice of the nurse at the public health centre.

Introduction: Every year about 450 women in Sweden are diagnosed with cervical cancer, almost 200 die and thousands undergo surgery because of cell changes in the cervix. A HPV infection can lead to cervical cancer and therefor costs for the society. The implementation of a vaccination program against HPV is a way to avoid these costs. Aim: The study aimed to calculate the economic impact of the HPV- vaccination program for children in Sweden through a cost-benefit analysis. Method: In this analysis, status quo was compared with non-administration of the HPV-vaccine for the selected cohort of ten-years-old girls in Sweden.

Vaccination inom barnhälsovården är en procedur som i stort sett alla barn i Sverige utsätts för vid ett flertal tillfällen under uppväxten. Vaccinationsproceduren kan upplevas som ett övergrepp av barnet om proceduren inte genomförs på ett mognadsanpassat sätt med fokus på det enskilda barnets perspektiv. Tidiga upplevelser av smärta sätter spår hos barnen och påverkar deras smärtupplevelser senare i livet. Syftet var att undersöka hur sjuksköterskor inom barnhälsovård i Blekinge arbetade med smärtlindring av barn i samband med vaccination inom det allmänna vaccinationsprogrammet. Urvalsgruppen bestod av alla sjuksköterskor som regelbundet arbetade med barnhälsovård i Blekinge.

The Swine flu (H1N1) erupted in 2009 and wasquickly spread over the world and developed into a pandemic, with a great threat against people?s health. It was soon discovered that the H1N1?virus had a different character than the seasonal flu, since it especially affected younger individuals and the consequences from the disease were expected to be more severe. In Sweden it was decided to provide a free of charge vaccination against the H1N1-virus, and the Swedish vaccination ratiobecome relatively high compared to other countries.

Vaccination inom barnhälsovården är en procedur som i stort sett alla barn i Sverige utsätts för vid ett flertal tillfällen under uppväxten. Vaccinationsproceduren kan upplevas som ett övergrepp av barnet om proceduren inte genomförs på ett mognadsanpassat sätt med fokus på det enskilda barnets perspektiv. Tidiga upplevelser av smärta sätter spår hos barnen och påverkar deras smärtupplevelser senare i livet. Syftet var att undersöka hur sjuksköterskor inom barnhälsovård i Blekinge arbetade med smärtlindring av barn i samband med vaccination inom det allmänna vaccinationsprogrammet. Urvalsgruppen bestod av alla sjuksköterskor som regelbundet arbetade med barnhälsovård i Blekinge.

The Swine flu (H1N1) erupted in 2009 and wasquickly spread over the world and developed into a pandemic, with a great threat against people?s health. It was soon discovered that the H1N1?virus had a different character than the seasonal flu, since it especially affected younger individuals and the consequences from the disease were expected to be more severe. In Sweden it was decided to provide a free of charge vaccination against the H1N1-virus, and the Swedish vaccination ratiobecome relatively high compared to other countries.

Vaccination of fish can be assumed to cause pain. This study was designed to see if we can minimize the suffering of fish following vaccination. Fishes are cold-blooded animals and thus more primitive than warm-blooded animals. Despite this, many organs, e.g. the nervous system, have the same basic structure as that of other vertebrates. The fibre system for conducting pain is more diffuse than in humans.